Embryonic development in the nematode (roundworm) Caenorhabditis elegans, is being studied in an effort to understand how different cells acquire their specific fate. In particular, we using RNA interference to identify genetic pathways required for intestine formation.

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• Annotation of the A. tumefaciens C58 genome shows two copies of proC. Which of the two copies provides the pyrroline-5-carboxylate reducatase activity to the bacterium? Both? Neither? The focus of this module will be to identify the functional copy of the proC gene.

• Annotation of the A. tumefaciens C58 genome shows two copies of proC. Which of the two copies provides the pyrroline-5-carboxylate reducatase activity to the bacterium? Both? Neither? The focus of this module will be to identify the functional copy of the proC gene.

• Annotation of the A. tumefaciens C58 genome shows two copies of proC. Which of the two copies provides the pyrroline-5-carboxylate reducatase activity to the bacterium? Both? Neither? The focus of this module will be to identify the functional copy of the proC gene.

• Annotation of the A. tumefaciens C58 genome shows two copies of proC. Which of the two copies provides the pyrroline-5-carboxylate reducatase activity to the bacterium? Both? Neither? The focus of this module will be to identify the functional copy of the proC gene.

Automated genome annotation indicates the presence of PHB Bioysynthetic genes in Agrobacterium tumefaicens C58, Agrobacterium radiobacter K84, Agrobacterium vitis S4 & Agrobacterium rhizogenes A4. This project will determine if the PHB biosynthetic genes in Agrobacterium species are functional.

• Annotation of the A. tumefaciens C58 genome shows two copies of argE. Which of the two copies provides the acetylornithine deacetylase activity to the bacterium? Both? Neither? The focus of this module will be to identify the functional copy of the argE gene.

• Annotation of the A. tumefaciens C58 genome shows two copies of argE. Which of the two copies provides the acetylornithine deacetylase activity to the bacterium? Both? Neither? The focus of this module will be to identify the functional copy of the argE gene.

• Annotation of the A. tumefaciens C58 genome shows two copies of argE. Which of the two copies provides the acetylornithine deacetylase activity to the bacterium? Both? Neither? The focus of this module will be to identify the functional copy of the argE gene.

• Annotation of the A. tumefaciens C58 genome shows two copies of argE. Which of the two copies provides the acetylornithine deacetylase activity to the bacterium? Both? Neither? The focus of this module will be to identify the functional copy of the argE gene.

In Silico bioinformatic analysis of duplicated genes in alphaproteobacteria. Students will independently investigate the similarities and differences between multiple copy genes that, by annotation, are predicted to have the same function.

• Shotgun Sequencing = Gap Filling = Genome Finishing = Annotation = Functional Genomics
• Contigs obtained from initial genome sequencing assembly must be arranged in the correct order and the intervening regions of DNA determined via a process referred to as "gap filling".

• Shotgun Sequencing = Gap Filling = Genome Finishing = Annotation = Functional Genomics
• Contigs obtained from initial genome sequencing assembly must be arranged in the correct order and the intervening regions of DNA determined via a process referred to as "gap filling".

• Shotgun Sequencing = Gap Filling = Genome Finishing = Annotation = Functional Genomics
• Contigs obtained from initial genome sequencing assembly must be arranged in the correct order and the intervening regions of DNA determined via a process referred to as "gap filling".